Thanks to a tip from @yojibee, I just tried and then immediately purchased AppZapper. Most excellent for uninstalling software that doesn't want to be uninstalled—like the resource-hogging Adobe Reader and Adobe Update. My MacBook Pro now starts up waaay faster.
From the AppZapper site:
AppZapper is for people who want to confidently try new apps while knowing they can uninstall them easily. Drag one or more unwanted apps onto AppZapper and watch as it finds all the extra files and lets you delete them with a single click.Highly recommended.
Update: Already referred another customer. Where's my commission? :-)

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